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Pseudoaneurysm vs True Aneurysm


Differences Between a Pseudoaneurysm and a True Aneurysm

True Aneurysm

A localized dilation of an artery involving all three layers of the vessel wall: intima, media, and adventitia.


Pseudoaneurysm (False Aneurysm)

A contained rupture of the arterial wall where blood leaks out and is held by surrounding tissues, not by the full vessel wall layers.



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Pathophysiology


True Aneurysm


Vessel wall weakens → gradual dilation


Wall structure remains intact


Common in chronic conditions



Pseudoaneurysm


Disruption of vessel wall → blood escapes


Forms a pulsatile hematoma communicating with artery


Wall is formed by fibrous tissue or surrounding structures




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Structural Difference


Feature True Aneurysm Pseudoaneurysm


Vessel wall layers All 3 layers intact Not intact

Wall composition Native arterial wall Surrounding tissue / thrombus

Neck Broad Narrow neck




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Common Causes


True Aneurysm


Atherosclerosis (most common)


Hypertension


Connective tissue disorders (e.g., Marfan syndrome)


Degenerative changes



Pseudoaneurysm


Trauma


Iatrogenic (post catheterization, procedures)


Infection


Surgical complications




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Common Sites


True Aneurysm


Abdominal aorta (AAA)


Thoracic aorta


Popliteal artery



Pseudoaneurysm


Femoral artery (post catheterization)


Radial artery


Anastomotic surgical sites




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Clinical Features


True Aneurysm


Often asymptomatic


May present as pulsatile mass


Risk of rupture if large



Pseudoaneurysm


Painful, tender swelling


Pulsatile mass with bruit


Rapid expansion more common




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Imaging Findings


True Aneurysm


Uniform dilation


Intact vessel wall


No “neck”



Pseudoaneurysm


“Yin-yang sign” on Doppler


Narrow neck connecting to artery


To-and-fro flow pattern




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Complications


True Aneurysm


Rupture


Thrombosis


Embolization



Pseudoaneurysm


Rupture (higher acute risk)


Compression of nearby structures


Infection




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Management


True Aneurysm


Surveillance if small


Surgical repair or EVAR if large or symptomatic



Pseudoaneurysm


Ultrasound-guided compression


Thrombin injection


Surgical repair if unstable




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Key Exam Pearls


True aneurysm = all vessel wall layers involved


Pseudoaneurysm = contained rupture with narrow neck


Yin-yang sign → classic for pseudoaneurysm


Post-procedure pulsatile swelling → think pseudoaneurysm




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One-Line Summary


True aneurysm is a dilated intact vessel, while pseudoaneurysm is a contained arterial rupture outside the vessel wall.


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