The most dangerous ECGs don’t always have the biggest ST elevation.
If you’re staring at V2–V3 trying to decide between Early Repolarization and a subtle LAD occlusion, stop looking at the ST segment and look at the Terminal QRS.
What is Terminal QRS Distortion? It’s a binary finding. In V2 or V3, ask yourself:
Is the S-wave gone?
Is the J-wave gone?
If the answer to both is YES, you are looking at Grade III ischemia.
The Stats:
Specificity: ~100% vs. Early Repolarization. BER simply doesn’t do this.
Sensitivity: ~20–35%. It won’t catch every STEMI, but when it’s there, it’s a “rule-in” sign.
Risk: Associated with larger infarct size (CMR-proven) and higher rates of heart failure.
The Logic: This is depolarization failing in real-time. Severe ischemia slows conduction so much that the end of the QRS gets “swallowed” by the repolarization phase.
Takeaway: Millimeters can lie. Morphology rarely does. If the S-wave is missing in the anterior leads, call the lab.

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