M-Mode Echocardiography: Normal Values and Key Diagnostic Findings
What is M-Mode in Echocardiography?
M-Mode (Motion mode) is a one-dimensional echocardiographic technique that records the motion of cardiac structures along a single ultrasound line over time. It provides:
Excellent temporal resolution
Precise linear measurements
Accurate assessment of valve motion
LV dimension and wall thickness quantification
Although 2D and Doppler imaging are routine, M-mode remains essential for standard chamber measurements and subtle motion abnormalities.
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Standard M-Mode Views
1. Parasternal Long Axis (PLAX) – LV Measurements
Cursor placed perpendicular to LV long axis at the level of mitral leaflet tips.
Measurements Taken:
IVSd (Interventricular septal thickness in diastole)
LVIDd (LV internal diameter in diastole)
LVIDs (LV internal diameter in systole)
LVPWd (Posterior wall thickness in diastole)
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Normal Adult LV M-Mode Values (ASE-Based)
LV Dimensions
LVIDd
Men: 4.2 – 5.8 cm
Women: 3.8 – 5.2 cm
LVIDs
Men: 2.5 – 4.0 cm
Women: 2.2 – 3.5 cm
Wall Thickness
IVSd: 0.6 – 1.0 cm
LVPWd: 0.6 – 1.0 cm
LV Systolic Function
Fractional Shortening (FS): 25 – 45%
Formula:
FS = (LVIDd − LVIDs) / LVIDd × 100
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Aortic Root & Left Atrium (PLAX M-Mode)
Normal Values:
Aortic root: 2.0 – 3.7 cm
Left atrial diameter:
Men: ≤ 4.0 cm
Women: ≤ 3.8 cm
LA/Ao ratio in children: < 1.3
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Mitral Valve M-Mode
Normal Pattern
M-shaped anterior leaflet
E wave > A wave
E-F slope normal
Key Abnormal Findings
1. Reduced E-F slope → Mitral stenosis
2. Increased EPSS (>7 mm) → LV systolic dysfunction
3. Anterior leaflet doming → Rheumatic MS
4. Diastolic fluttering → Aortic regurgitation
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Aortic Valve M-Mode
Normal
Box-like opening pattern
Symmetrical cusp separation
Abnormal
Reduced separation → Aortic stenosis
Eccentric closure line → Bicuspid valve
Fine oscillations → Vegetation
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Common Pathological Patterns on LV M-Mode
1. Concentric LVH
Increased IVSd and LVPWd
Normal or reduced cavity size
Causes: Hypertension, Aortic stenosis
2. Dilated Cardiomyopathy
Increased LVIDd and LVIDs
Reduced fractional shortening
3. Asymmetric Septal Hypertrophy
IVSd > LVPWd (ratio > 1.3)
Suggestive of HCM
4. Paradoxical Septal Motion
Seen in:
LBBB
RV pacing
Post cardiac surgery
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Right Ventricular Assessment (Subtle Role of M-Mode)
TAPSE (Tricuspid Annular Plane Systolic Excursion)
Measured using M-mode in apical 4-chamber view.
Normal: ≥ 17 mm
Reduced in RV systolic dysfunction
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Practical Tips for Accurate M-Mode
Always ensure cursor is perpendicular
Measure at end-diastole (R wave)
Avoid oblique cuts
Average over 3 cardiac cycles (5 in AF)
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Clinical Importance of M-Mode in Modern Practice
Despite advanced imaging techniques, M-mode remains valuable because of:
Superior temporal resolution
Reproducible LV measurements
Quick bedside assessment
Essential component of ASE chamber quantification guidelines
M-mode is simple, fast, and highly informative when used correctly.

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