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L-Wave on Echocardiography: The Hidden Doppler Clue to Advanced Diastolic Dysfunction

What is L Wave in Echocardiography
L Wave on Echo

L-Wave on Echocardiography: The Hidden Doppler Clue to Advanced Diastolic Dysfunction

What is the L-Wave?

The L-wave is a mid-diastolic transmitral flow wave seen on pulsed-wave Doppler echocardiography, occurring between the E-wave (early diastolic filling) and A-wave (atrial contraction).


It represents continued left ventricular (LV) filling during diastasis and is not a normal finding in adults. Its presence strongly suggests diastolic dysfunction with elevated left ventricular filling pressures.



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Normal Mitral Inflow Pattern (Recap)


Normal transmitral Doppler flow consists of:


E-wave → Early rapid LV filling due to pressure gradient between LA and LV


Diastasis → Minimal or no flow


A-wave → Atrial contraction



There is no mid-diastolic flow in normal physiology.



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What Causes the L-Wave?


The L-wave appears when:


LV relaxation is impaired but


LA pressure remains persistently elevated



This creates a renewed pressure gradient during mid-diastole, allowing additional flow into the LV.


Major Causes


1. Elevated LV filling pressures


Advanced diastolic dysfunction


Restrictive physiology


Heart failure with preserved EF (HFpEF)




2. Bradycardia


Prolonged diastasis allows time for mid-diastolic flow to occur




3. Atrial Fibrillation


A-wave absent


L-wave may be difficult to distinguish but can still occur due to high LA pressure






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Pathophysiology Explained Simply


Impaired LV relaxation → reduced early filling


Elevated LA pressure → persistent pressure gradient


During diastasis, blood continues to flow into LV → L-wave



This indicates advanced diastolic disease, not just mild relaxation abnormality.



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Echocardiographic Features of the L-Wave


Seen on pulsed-wave Doppler at mitral leaflet tips


Appears after E-wave and before A-wave


Best visualized at slow heart rates


Often associated with:


Enlarged left atrium


Reduced e′ velocity on tissue Doppler


Elevated E/e′ ratio


Pulmonary venous diastolic dominance





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Clinical Significance of the L-Wave


The L-wave is a marker of elevated filling pressures and has important prognostic implications.


Associated Conditions


Advanced diastolic dysfunction (Grade II–III)


HFpEF


Restrictive cardiomyopathy


Acute decompensated heart failure



Prognostic Value


Associated with worse functional class


Predicts heart failure hospitalization


Indicates poor LV compliance




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L-Wave vs Other Diastolic Patterns


Feature L-Wave Normal Restrictive Filling


Mid-diastolic flow Present Absent Often present

Filling pressure High Normal Very high

Prognosis Unfavorable Normal Poor




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Practical Tips for Detection


Reduce sweep speed to clearly visualize diastasis


Look carefully in bradycardic patients


Correlate with:


Tissue Doppler e′


LA size


TR velocity



In AF, interpret with caution due to beat-to-beat variability




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Key Take-Home Messages


L-wave = mid-diastolic LV filling


Strong indicator of elevated filling pressures


Seen in advanced diastolic dysfunction


Common in HFpEF and restrictive physiology


Has important diagnostic and prognostic value


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For more infographics and cardiology education, visit:

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