π§ How to Evaluate HEADACHE
Headache is one of the most common reasons for medical visits—but also one of the easiest to misjudge. A systematic approach helps you immediately distinguish benign headaches from life-threatening ones.
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1️⃣ Start With the Most Important Step: Is it Dangerous?
Always rule out secondary causes first.
π¨ Red Flags — SNOOP10
If ANY of these are present, think secondary headache:
S – Systemic symptoms (fever, weight loss) or systemic disease (HIV, cancer)
N – Neurological symptoms/signs (focal deficits, altered sensorium)
O – Onset sudden (thunderclap, reaches peak in < 1 min)
O – Older age (>50 years)
P – Pattern change or first/worst headache
Plus “10 extras”
Precipitated by Valsalva/exertion/cough
Papilledema
Positional headache
Pregnancy/postpartum
Painful eye + autonomic symptoms
Post-trauma
Progressive worsening
Paroxysmal with exertion/sex
Poor immunity (steroids, chemo)
Pharmacologic causes (anticoagulants → bleed)
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2️⃣ Take a Structured History – The 7 Key Questions π
1. Onset
Sudden (→ SAH, CVT, dissection)
Gradual (→ migraine, tension)
2. Location
Hemicranial → Migraine
Orbital → Cluster / angle-closure glaucoma
Occipital → Cervicogenic / hypertension / posterior circulation
3. Duration & frequency
Seconds → Neuralgia
30 min–3 hrs → Cluster
4–72 hrs → Migraine
Daily/continuous → NDPH, MOH
4. Character
Pulsatile → Migraine
Pressing/tight → Tension-type
Stabbing/shock-like → Trigeminal neuralgia
5. Associated symptoms
Nausea/vomiting, photophobia → Migraine
Tearing, rhinorrhea → Trigeminal autonomic cephalalgias
Fever/rigidity → Meningitis
Vision loss/Jaw claudication → GCA
6. Triggers
Stress, sleep deprivation, menses → Migraine
Alcohol → Cluster
Cough/exertion → Structural lesion
7. Medication use
Frequent NSAIDs, triptans → Medication-overuse headache (MOH)
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3️⃣ Focused Examination
General exam
Fever (meningitis)
BP (HTN crisis)
Scalp tenderness (GCA)
Neurological exam
Cranial nerves
Motor/sensory
Gait, reflexes
Meningeal signs
Fundoscopy
Papilledema
Hemorrhages
Optic pallor
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4️⃣ When to Order Investigations?
Neuroimaging
Non-contrast CT head—first-line for:
Thunderclap headache
Trauma
Focal neuro deficits
Suspected raised ICP
MRI brain
Persistent headaches with normal CT
Suspicion of tumor, CVT, posterior fossa lesions
Chronic progressive headaches
MRV/CTV
Suspected cerebral venous thrombosis
(postpartum, OCP use, dehydration)
Lumbar puncture
Do after normal CT if:
Suspicion of SAH but CT negative
Meningitis/encephalitis
Idiopathic intracranial hypertension (opening pressure)
Blood tests
ESR/CRP → Suspect GCA (>50 years)
CBC → Infection, anemia
Pregnancy test → If imaging needed
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5️⃣ Differentiate Common Primary Headaches
π― Migraine
Unilateral throbbing
Nausea/vomiting
Photophobia/phonophobia
± Aura
Worse with routine activity
π― Tension-Type
Bilateral, band-like pressure
Mild–moderate
No nausea/vomiting
Stress-related
π― Cluster Headache
Severe, unilateral orbital pain
Tearing, rhinorrhea, red eye
Occurs in clusters at same time daily
“Suicide headache”
π― Medication-Overuse Headache
Daily near-constant headache
Using analgesics >10–15 days/month
Improves after withdrawal
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6️⃣ Life-Threatening Causes Not to Miss π
Subarachnoid hemorrhage
Meningitis/Encephalitis
Cerebral venous thrombosis
Temporal arteritis
Acute angle-closure glaucoma
Hypertensive emergency
Intracranial tumor/mass effect
Carbon monoxide poisoning
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7️⃣ Putting It All Together: The FAST Algorithm
F – Flag?
Any red flags → URGENT imaging/LP.
A – Ask structured questions
Onset, location, duration, character, associated symptoms, triggers.
S – Scan when needed
CT → emergencies
MRI → subacute/chronic cases
T – Treat appropriately
Primary headaches → symptomatic + preventive therapy
Secondary → treat underlying cause
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✅ Summary Table (Ultra High-Yield)
Step What You Do
1. Rule out danger SNOOP10 red flags
2. History Onset, location, character, frequency, triggers, meds
3. Examination Neuro + fundus + systemic
4. Investigations CT/MRI/LP based on suspicion
5. Diagnose Migraine, TTH, cluster, MOH, or secondary cause
6. Treat Targeted therapy or emergency management

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