Defibrillator implantation in patients with non-ischemic systolic heart failure - The New England Journal of Medicine - 2016

Brief Summary:

In patients with non-ischemic cardiomyopathy with LVEF ≤35% with symptomatic heart failure, ICDs did not result in an overall mortality benefit versus standard care after 5.5 years of follow up. ICD implantation did result in a 3% absolute reduction in sudden cardiac death that was somewhat mitigated by device-related morbidity including an absolute 1.5% increase in device-related infection.

Reference: http://www.ncbi.nlm.nih.gov/pubmed/27571011