Transcatheter Mitral Valve Repair in Patients with Heart Failure - The New England Journal of Medicine - 2018

Brief Summary:

In patients with HFrEF (mean LVEF 31%, 61% ischemic) resulting in moderate-severe or severe functional MR, percutaneous mitral valve repair results in a 32.1% absolute reduction in heart failure hospitalization at 2 years compared to medical therapy alone. Device-based therapy was also associated with a 16% absolute reduction in all cause death. At 1 year, device-related complications occurred at a rate of 3.4%, meeting pre-specified criteria for safety.