Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure - The Lancet - 1999
Brief Summary:
In patients with symptomatic HFrEF with EF ≤40%, long acting metoprolol led to a 34% reduction in all cause mortality.Reference: http://www.ncbi.nlm.nih.gov/pubmed/10376614
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