ISAR-TRIPLE

Duration of triple therapy in patients requiring oral anticoagulation after drug-eluting stent implantation - J Am Coll Cardiol - 2015

Brief Summary:

In patients requiring oral anticoagulation (OAC) for a separate indication undergoing drug-eluting stent (DES) placement after coronary intervention, six weeks of clopidogrel therapy in addition to aspirin and OAC is not associated with improved net clinical outcomes compared to 6 months of clopidogrel therapy after 9 months. Both major bleeding risk and thrombotic risk appeared to be similar with either the shorter or longer duration of "triple therapy" over this limited period of follow-up.

Reference: http://www.ncbi.nlm.nih.gov/pubmed/25908066