COMET

Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial - The Lancet - 2003

Brief Summary:

In patients with HFrEF (EF ≤35%) and NYHA II-IV symptoms, Carvedilol reduced all-cause mortality compared to metoprolol tartrate.

Reference: http://www.ncbi.nlm.nih.gov/pubmed/12853193

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