SPYRAL HTN ON MED

Effect of renal denervation on blood pressure in the presence of antihypertensive drugs - The Lancet - 2018

Brief Summary:

Among patients with uncontrolled hypertension (office SBP 150-180mmHg and DBP ≥ 90mmHg as well as 24h ambulatory SBP 140-170mmHg) despite 1-3 antihypertensive medications, the addition of renal denervation to medical therapy results in a significant reduction in blood pressure at 6 months (reduction of 9mmHg in 24h ambulatory SBP and 6mmHg in DBP, with mean difference of -7.4mmHg systolic and -4.1mmHg compared to medical therapy alone, respectively). Medication adherence was about 60% in both groups.

Reference: http://www.ncbi.nlm.nih.gov/pubmed/29803589