PREDIMED

Primary prevention of cardiovascular disease with a mediterranean diet - The New England Journal of Medicine - 2013

Brief Summary:

In the initial 2013 publication, a Mediterranean diet with extra-virgin olive oil or nuts was thought to reduce rates of MI, CVA, or CV death in those at high risk for CV disease. In 2018, this trial was retracted and replaced for abnormalities in randomization. The updated publication documented similar findings but the authors were unable to confirm adherence to randomization schemes given missing documentation.

Reference: http://www.ncbi.nlm.nih.gov/pubmed/23432189