PLATO

Ticagrelor versus clopidogrel in patients with acute coronary syndromes - The New England Journal of Medicine - 2009

Brief Summary:

Compared to clopidogrel, ticagrelor significantly reduced the rate of CV death, MI, or stroke without an increase in the rate of overall major bleeding.

Reference:
http://www.ncbi.nlm.nih.gov/pubmed/19717846