Dr. Usman's Cardiology Notes

 Treatment of cardiac amyloidosis involves: 1. Stabilizing amyloid deposits: Tafamidis (stabilizes transthyretin) 2. Reducing amyloid production: Patisiran, Inotersen (for transthyretin amyloidosis) 3. Chemotherapy: For AL amyloidosis (e.g., daratumumab, bortezomib) 4. Heart failure management: Diuretics, ACE inhibitors, beta-blockers 5. Heart transplantation: In selected cases Treatment approach depends on the type of amyloidosis (e.g., transthyretin, AL, or others).

  Dr. Samuel J. Asirvatham's lecture on Ventricular Tachycardia (VT) provides a comprehensive review of the topic, covering the definition, mechanisms, diagnosis, and management of VT. The lecture is designed to help cardiology fellows and board-certified cardiologists prepare for certification exams. VT is defined and its mechanisms are discussed, including re-entry, triggered activity, and automaticity. Re-entry occurs when an electrical impulse recurrently activates the ventricle, while triggered activity and automaticity can lead to abnormal electrical activity. The diagnosis of VT is covered, including electrocardiogram (ECG) characteristics such as wide QRS complexes, AV dissociation, and fusion beats. The clinical presentation of VT is also discussed, including symptoms and signs. The management of VT is reviewed, including acute management with cardioversion, anti-arrhythmic medications, and ACLS protocols. Chronic management options are also discussed, including implantabl...