Dr. Usman's Cardiology Notes

 

Following are some good references for the Modified Sgarbossa Criteria (MSC) for diagnosing myocardial infarction in the presence of wide QRS (e.g. Left Bundle Branch Block — LBBB — or paced rhythm): ✅ What is the Modified Sgarbossa Criteria The Modified Sgarbossa Criteria was proposed by Stephen W. Smith et al (2012) to improve the diagnostic accuracy of the original Sgarbossa Criteria in patients with LBBB or ventricular paced rhythm.  The key modification is replacing the “absolute ST-elevation ≥ 5 mm in a lead with a negative (discordant) QRS” rule with a proportional rule based on the ST-segment to S-wave amplitude ratio (ST/S ratio).  Using a proportional cutoff (e.g. ST/S ≤ –0.25, or ST elevation ≥ 25% of the depth of the S wave) improves sensitivity compared with the original fixed-mm rule, while maintaining high specificity.  --- 📚 Key Literature / References Reference / Source Notes / Findings Smith SW, Dodd KW, Henry TD, Dvorak DM, Pearce LA. “Diagnosis of ST-...

  True Aneurysm vs Pseudoaneurysm: Understanding the Difference in a Way That Actually Makes Sense When you hear the word aneurysm, it often brings a sense of alarm — and rightly so. But in clinical practice, not all aneurysms behave the same way. Two terms frequently come up that sound similar but are worlds apart in meaning and management: True Aneurysm and Pseudoaneurysm. Key Difference: True aneurysm = the vessel wall stretches out but stays whole. Pseudoaneurysm = the vessel wall actually tears, and a fake sac forms outside. Let’s break them down in a simple, relatable way — the kind you’d actually explain to a friend or even a patient. --- Imagine the Blood Vessel as a House Wall… 🏠 A True Aneurysm is like a wall that has stretched out… but hasn’t broken. All three layers of the arterial wall — intima, media, and adventitia — balloon outwards together. Think of it like an old wall bulging because of water damage… the wall is still intact, but it’s weak. 💥 A Pseudoaneurysm i...

KEY FACTS OF Peripartum Cardiomyopathy - PPCM Peripartum Cardiomyopathy (PPCM): The Heart Condition Every Clinician Should Recognize Pregnancy is often described as a physiological stress test for the body. While most women adapt remarkably well, a small number develop a rare but potentially life-threatening cardiac condition known as Peripartum Cardiomyopathy (PPCM). Despite improved awareness, PPCM continues to be underdiagnosed—mainly because its symptoms mimic normal pregnancy-related discomforts. In this article, we explore what PPCM is, how it presents, why it happens, and why early recognition makes all the difference. --- What Is Peripartum Cardiomyopathy? Peripartum cardiomyopathy is an idiopathic form of heart failure characterized by left ventricular systolic dysfunction that develops during a very specific period: **✔ From the last month of pregnancy ✔ To up to 5 months after delivery** Women must not have had any prior structural heart disease, and the LVEF is typically ...

Understanding the Rentrop Classification: A Guide to Coronary Collateral Circulation When a coronary artery becomes completely blocked, the heart doesn't always lose all blood supply to that area. Thanks to collateral circulation, smaller vessels can sometimes step in to provide alternate routes for blood flow. The Rentrop classification system helps cardiologists assess just how well these backup pathways are working during coronary angiography. What is the Rentrop Classification? Developed to standardize the assessment of coronary collateral vessels, the Rentrop classification grades collateral circulation on a scale from 0 to 3. This grading system is particularly important when evaluating patients with chronic total occlusions or severe coronary artery disease. The presence and quality of collateral circulation can significantly impact patient outcomes, treatment decisions, and prognosis. The Four Grades Explained Grade 0: No Visible Collaterals In Grade 0, there are no visible...

  HOMA-IR Clinical uses and interpretation of HOMA-IR? HOMA-IR is a simple surrogate marker used to estimate insulin resistance, calculated from fasting glucose and fasting insulin. ✅ Normal Values and Interpretation There is no universal cut-off. Cutoffs vary by population, ethnicity, and assay used. But clinical practice generally uses: HOMA-IR Value Interpretation < 1.0. Excellent insulin sensitivity 1.0 – 1.9. Normal insulin sensitivity 2.0 – 2.5 Early insulin resistance 2.5 – 3.9. Moderate insulin resistance ≥ 4.0 Severe insulin resistance / hyperinsulinemic state For South Asian / Middle Eastern populations, even HOMA-IR > 2.0 already suggests significant insulin resistance. Clinical Uses of HOMA-IR HOMA-IR is most useful for: 1) Diagnosing insulin resistance Especially in: Obesity Metabolic syndrome Acanthosis nigricans PCOS Pre-diabetes NAFLD / NASH Because fastin...

 Wells Criteria for Pulmonary Embolism: A Comprehensive Clinical Guide  Introduction The Wells Criteria for Pulmonary Embolism (PE) is a validated clinical prediction rule designed to help healthcare providers estimate the probability of PE in patients presenting with suggestive symptoms. Developed by Dr. Philip Wells and colleagues, this scoring system has become an essential tool in emergency departments and outpatient settings worldwide, helping clinicians make informed decisions about diagnostic testing and management. ## Understanding Pulmonary Embolism Pulmonary embolism occurs when a blood clot, typically originating from the deep veins of the legs, travels through the bloodstream and lodges in the pulmonary arteries, blocking blood flow to the lungs. PE is a life-threatening condition that requires prompt recognition and treatment. However, its symptoms can be nonspecific, making diagnosis challenging. Common presenting symptoms include sudden shortness of breath, ches...