Triad of Hypothyroidism Hypothyroidism is a common endocrine disorder characterized by reduced thyroid hormone production, leading to a generalized slowing of metabolic processes. Although the clinical presentation can be broad and nonspecific, a classic and easily remembered clinical combination is the Triad of Hypothyroidism, which includes weight gain, fatigue, and cold intolerance. Recognizing this triad can help clinicians suspect hypothyroidism early and prompt appropriate laboratory evaluation. --- Weight Gain Weight gain in hypothyroidism is primarily due to reduced basal metabolic rate and accumulation of interstitial fluid rather than true fat deposition alone. Thyroid hormones normally regulate energy expenditure and lipid metabolism. When hormone levels fall, metabolic activity decreases, resulting in gradual weight gain. Patients often report difficulty losing weight despite unchanged diet or activity levels. --- Fatigue Fatigue is one of the most common presen...
Dr. Usman's Cardiology Notes
Cardiology Notes: Clinical Cases including ECG, Echocardiography, Cath, and MOCK Exams to sharpen your cardiology data interpretation skills. Healthcare is stressful!!! Learning cardiology shouldn't be !!!